Making a hearty and tasty meal doesn’t have to be hard. Casseroles with ground beef are perfect when you want something warm and filling that brings everyone together. Whether you’re feeding the family, planning ahead, or just craving comfort food, this guide will help you create a delicious ground beef casserole with ease.
Why We Love These Casseroles with Ground Beef
You’re not alone if casseroles remind you of family dinners and warm gatherings. These recipes aren’t just simple—they’re a celebration of flavor, texture, and heartwarming tradition.
- One-Pan Wonder – Everything cooks in one dish. That means fewer dirty dishes and more time to relax.
- Affordable Ingredients – You can pull this together with staples you already have.
- Endlessly Adaptable – Toss in your favorite veggies, swap out sauces, or mix up the cheese.
- Make-Ahead Friendly – Perfect for freezer meals or next-day lunches.
- Crowd-Pleaser – Even picky eaters can’t resist a cheesy, beefy bake.
These casseroles offer comfort without complication—making them a go-to recipe in any kitchen.

Ingredients
To get you started, here’s a simple ingredient list for a traditional casserole that never fails to please:
Ground Beef – The main ingredient that adds flavor and makes the casserole filling. Lean ground beef works best.
Pasta – Any type like elbow macaroni or penne. It soaks up the sauce and holds everything together.
Tomato Sauce – Adds moisture and richness to the casserole, making it flavorful.
Cheese – Shredded mozzarella or cheddar, for a melty, golden top layer.
Onion & Garlic – These give the dish extra flavor and aroma.
Italian Seasoning – A mix of herbs to add a savory, aromatic touch.
Salt & Pepper – To season and bring out the flavors of the other ingredients.
Each ingredient brings depth to the dish while keeping the process uncomplicated. You can tweak this base recipe based on dietary preferences or what you have in your pantry.
How to Make Casseroles with Ground Beef
Preheat your oven to 375°F (190°C).
Cook the pasta just until al dente. Drain and set aside.
In a large skillet, brown the ground beef and onion over medium heat. Drain any excess fat.
Stir in tomato sauce, garlic powder, salt, and pepper. Let it simmer for a few minutes.
Mix the cooked pasta with the beef mixture. Ensure everything is well combined.
Pour the mixture into a greased casserole dish.
Sprinkle cheese evenly over the top.
Bake uncovered for 20-25 minutes, until the cheese is melted and bubbly.
Let it rest for 5 minutes before serving to help it set.
With just a few simple steps, you have a flavorful casserole that feels like home.

Expert Tips for the Best Ground Beef Casseroles
You can elevate your casserole game with just a few smart kitchen strategies:
Season every layer – Don’t just rely on the sauce. Taste and adjust throughout.
Use a mix of cheeses – Combining sharp cheddar with mozzarella creates gooey richness.
Don’t overcook the pasta – It continues to cook in the oven, so keep it slightly firm.
Let the dish rest – Five to ten minutes gives the casserole time to firm up for clean slices.
Bake uncovered – This lets the top get golden and irresistible.
These techniques help ensure your casserole isn’t just good—it’s unforgettable.
Variations to Try
The beauty of casseroles with ground beef is how easily they adapt to different cuisines and dietary needs:
Tex-Mex Twist – Add taco seasoning, black beans, and top with crushed tortilla chips.
Italian-Inspired – Swap in marinara, use penne pasta, and add Italian herbs.
Low-Carb Option – Replace pasta with riced cauliflower or spiralized zucchini.
Cheeseburger Casserole – Mix in mustard, ketchup, pickles, and a sprinkle of sesame seeds on top.
Every variation opens the door to something new while staying grounded in the familiar comfort of ground beef.
Serving Suggestions for Ground Beef Casseroles
Pair your casserole with simple sides to create a balanced, satisfying meal:
Green Salad – Freshness and crunch to contrast the warm, cheesy bake.
Garlic Bread or Dinner Rolls – Perfect for soaking up extra sauce.
Roasted Veggies – Add a serving of colorful nutrients with broccoli, carrots, or green beans.
Fruit Salad – For a light, refreshing finish.
A thoughtful pairing makes the meal feel complete and well-rounded.
More Beef recipes you will love!
Frequently Asked Questions about Casseroles with Ground Beef
What is the best type of ground beef for casseroles?
For rich flavor without too much grease, go for 80/20 ground beef. If you’re aiming for leaner, 90/10 works well but may need a touch more seasoning or oil.
Can you make casseroles with ground beef ahead of time?
Absolutely. You can assemble the casserole, cover it tightly, and refrigerate it for up to 24 hours before baking. Great for prepping meals in advance.
How can I make this recipe gluten-free?
Just substitute the regular pasta with a gluten-free version and make sure your sauces and seasonings are certified gluten-free.
Can I use leftover cooked ground beef?
You sure can. This cuts down prep time—just mix it in with the pasta and sauce before baking.

Casserole with Ground Beef
Equipment
- Large Skillet
- Casserole Dish
- Oven
Ingredients
Main Ingredients
- 1 lb ground beef 80/20 for richer flavor
- 2 cups elbow pasta uncooked
- 15 oz tomato sauce
- 1 small onion finely chopped
- 1 cup cheddar cheese shredded
- 1 teaspoon garlic powder
- salt and pepper to taste
Optional Add-ins
- 1 cup chopped bell peppers
- 1/2 cup frozen corn or peas
- 1/2 cup sliced mushrooms
- 1/4 teaspoon red pepper flakes for heat
Instructions
- Preheat oven to 375°F (190°C).
- Cook pasta just until al dente. Drain and set aside.
- In a large skillet, brown the ground beef and chopped onion over medium heat. Drain excess fat.
- Stir in tomato sauce, garlic powder, salt, and pepper. Simmer for a few minutes.
- Combine beef mixture with cooked pasta and mix thoroughly.
- Transfer mixture to a greased casserole dish. Top evenly with shredded cheese.
- Bake uncovered for 20–25 minutes, until cheese is melted and bubbly.
- Let rest for 5 minutes before serving.