Bring a large pot of salted water to a boil. Cook the bowtie pasta until al dente, then drain and set aside.
Heat a large skillet over medium heat. Add ground beef or turkey, cooking thoroughly and breaking it up as it browns. Drain any excess fat.
Return the cooked meat to the pan and add the drained pasta on top. Pour in the marinara sauce, salt, garlic powder, Italian seasoning, and crushed red pepper. Stir to combine.
Add the shredded mozzarella and sour cream (or Greek yogurt) into the pan. Stir over low heat until the cheese melts and the sauce becomes creamy.
Adjust seasoning with additional salt and pepper as needed. Serve hot, dividing into 8 portions.
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Notes
Store leftovers in an airtight container in the refrigerator for up to 3-4 days.